[1]李殿富.核素显像识别存活心肌的临床应用进展[J].国际放射医学核医学杂志,2003,27(3):105-106110.
 LI Dian-fu.Clinical advances of nuclear imaging in the assessment of viable myocardium[J].International Journal of Radiation Medicine and Nuclear Medicine,2003,27(3):105-106110.
点击复制

核素显像识别存活心肌的临床应用进展(/HTML)
分享到:

《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
27
期数:
2003年第3期
页码:
105-106110
栏目:
综述
出版日期:
1900-01-01

文章信息/Info

Title:
Clinical advances of nuclear imaging in the assessment of viable myocardium
作者:
李殿富
210029 南京, 南京医科大学第一附属医院心脏科
Author(s):
LI Dian-fu
Department of Cardiology, the First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China
关键词:
存活心肌核素显像冠心病
Keywords:
viable myocardiumSPECTcoronary artery disease
分类号:
R817.4
摘要:
存活心肌的判断对冠心病患者治疗方案的选择及预后十分重要。201Tl再注射法、硝酸甘油介入的静息99Tcm-sestamibi法增强了心肌灌注核素体层显像对存活心肌的检测能力,门控SPECT技术能在评估心肌灌注的同时计算LVEF(左心室射血分数)、局部室壁运动和局部室壁增厚率,具有符合线路的SPECT可以进行心肌代谢显像及灌注显像,其对存活心肌的检测能力可能接近于PET,而检查费用可大大降低。
Abstract:
The assessment of myocardial viability is of particular importance in determining the appropriate managements and making accurate prognoses in coronary artery disease patients. The new algorithms such as 201Tl rest/redistribu-tion and nitroglycerin-augmented rest 99Tcm-sesbamibi and the recently performed gated SPECT, which could make a combined assessment of myocardial perfusion and LV function, have greatly enhanced the use of myocardial perfusion SPECT in the assessment of myocardial viability. The coincidence SPECT, which can perform myocardial perfusion and glucose metabolism imaging spontaneously, is nearly as powerful as PET but is less costly in the myocardial viability assessment.

参考文献/References:

[1] Frans J, Wackers TH, Soufer R, et al. Heart Diease[M]. 6th ed. Philadelphea:Saunders, 2001. 273-322.
[2] Batista JF, Pereztol O, Valdes JA, et al. Improved detec-tion of myocardial perfusion reversibility by rest-nitroglycerin Tc-99m-MIBI:comparison with Tl-201 reinjection[J]. J Nucl Cardiol, 1999, 6:480-486.
[3] Khouri F, Narula J. Radionuclide imaging for the assess-ment of myocardial viability in chronic LV dysfunction[J]. Echocardiography, 2000, 17:605-612.
[4] Sciagra R, Bist G, Santoro GM, et al. Comparison of baseline-nitrate technetium-99m sestamibi with rest-redistribution thallium-201 tomography in detecting viable hibernating myocardium and predicting post-revascularization recovery[J]. J Am Coll Cardiol, 1997, 30:384391.
[5] Bax JJ, poldermans D Elhendy A, et al. SH.Sinsitivity, specificity and predictive accuracies of various noninvasive techniques for detecting hihernating myocardium[J].Curr Probl Cardiol, 2001, 27:114-173.
[6] Hendel RC, Corbett JR, Cullom SJ, et al. The value and practice of attenuation correction for myocardial perfusion SPECT imaging:a joint position statement from theAmerican Society of Nuclear Cardiology and the Society of Nuclear Medicine[J]. J Nucl Cardiol, 2002, 9(1):135-143.
[7] Sharir T, Bacher-Stier C, Dhar S, et al. Post exercise regional wall motion abnormalities detected by Tc-99m sestamibi gated SPECT:a marker of severe coronary artery disease[J]. J Nucl Med, 1998, 39:87P-88P.
[8] Depuey EG.Major advances in single-photon emission com-puted tomography perfusion imaging[J]. Cardiol Rev, 2000, 8(1):40-48.
[9] Kloner RA. Stunned and hibernating myocardium[J]. Coro Art Dis, 2001,12:341-360.
[10] Bonow RO. Myocardial viability and prognosis in patients with ischemic left ventricular dysfunction[J]. J Am Coll Cardiol, 2002, 39:1159-1162.
[11] He Z, Verani M. Evaluation of myocardial perfusion imaging:should nitrates be used[J]. J Nucl Cardiol, 1998, 5:527-532.
[12] Danias PG, Ahlberg AW, Clark BA, et al. Combined assessment of myocardial perfusion and left ventricular function with exercise technetium-99m sestamibi gated single-photon emission computed tomography can differentiate between ischemic and nonischemic dilated car-diomyopathy[J]. Am J Cardiol, 1998, 82:1253-1258.
[13] Matsunari I, Yoneyama T, Kanayama S, et al. Phantom studies for estimation of defect size on cardiac 18F SPECT and PET:implications for myocardial viability assessment[J]. J Nucl Med. 2001, 42(10):1579-1585.
[14] Bax JJ, Visser FC, Poldermans D, et al. Relationship between preoperative viability and postoperative improvement in LVEF and heart failure symptoms[J]. J Nucl Med, 2001, 42(1):79-86.
[15] Berman DS, Hayes SW, Shaw LJ, et al. Recent advances in myocardial perfusion imaging[J]. Curr Pro Cardiol, 2001, 26:86-94.

相似文献/References:

[1]靳彩玲,范我.99Tcm-AnnexinV用于体内细胞凋亡显像的研究进展[J].国际放射医学核医学杂志,2005,29(1):23.
 JIN Cai-ling,FAN Wo.Advance of apoptosis imaging with 99Tcm labeled Annexin V[J].International Journal of Radiation Medicine and Nuclear Medicine,2005,29(3):23.
[2]刘晓梅,李冬雪,潘莉萍.核医学对放疗诱发的肾、脑、唾液腺等正常组织损伤的监测[J].国际放射医学核医学杂志,2005,29(4):166.
 LIU Xiao-mei,LI Dong-xue,PAN Li-ping.Nuclear medicine in the detection of radiation associated normal tissue damage of kidney, brain and salivary glands[J].International Journal of Radiation Medicine and Nuclear Medicine,2005,29(3):166.
[3]陈璟,吴华.核素炎症显像的研究进展[J].国际放射医学核医学杂志,2003,27(3):107.
 CHEN Jing,WU Hua.The development of radionuclide imaging of infection and inflammation[J].International Journal of Radiation Medicine and Nuclear Medicine,2003,27(3):107.
[4]何薇,蒋茂松.核素炎症定位显像在炎症性肠道疾病中的临床应用[J].国际放射医学核医学杂志,2001,25(1):3.
 HE Wei.Clinical evaluation of radiopharmaceuticals for the inflammatory localization of Crohn’s disease and ulcerative colitis[J].International Journal of Radiation Medicine and Nuclear Medicine,2001,25(3):3.
[5]朱小华.99Tcm标记annexin V进行体内凋亡显像的研究[J].国际放射医学核医学杂志,2000,24(2):51.
 ZHU Xiao-hua.The study about imaging of apoptosis with 99Tcm-labled annexin V[J].International Journal of Radiation Medicine and Nuclear Medicine,2000,24(3):51.
[6]罗锡圭.消化系统疾病核素检查的临床价值[J].国际放射医学核医学杂志,1998,22(1):17.
[7]陈璟,吴华.核素显像在乳腺癌诊治中的应用进展[J].国际放射医学核医学杂志,1998,22(6):252.
[8]马寄晓.甲状旁腺的核素显像[J].国际放射医学核医学杂志,1997,21(5):268.
[9]黄钢,赵惠杨.PET心肌代谢显像评价心肌梗塞区存活心肌[J].国际放射医学核医学杂志,1995,19(6):241.
[10]张佳胤.核素心肌显像在冠状动脉旁路移植术中的应用[J].国际放射医学核医学杂志,2005,29(4):152.
 ZHANG Jia-yin.Application of nuclear myocardial imaging in coronary artery bypass graft[J].International Journal of Radiation Medicine and Nuclear Medicine,2005,29(3):152.

备注/Memo

备注/Memo:
收稿日期:2002-09-05。
作者简介:李殿富(1965-),男,博士研究生,主要从事冠心病影像学研究。
更新日期/Last Update: 1900-01-01