[1]吕兑财.低剂量辐射兴奋效应及其机制[J].国际放射医学核医学杂志,2000,24(6):275-281.
 LU Duicai.Stimulative effects of low dose radiation and their mechanism[J].International Journal of Radiation Medicine and Nuclear Medicine,2000,24(6):275-281.
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低剂量辐射兴奋效应及其机制(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
24
期数:
2000年第6期
页码:
275-281
栏目:
综述
出版日期:
1900-01-01

文章信息/Info

Title:
Stimulative effects of low dose radiation and their mechanism
作者:
吕兑财
215007 江苏苏州, 苏州大学核医学院放射生物学教研室
Author(s):
LU Duicai
School of Nuclear Medicine Su Zhou University, Su Zhou JiangSu, China
关键词:
低剂量电离辐射兴奋效应天然放射性高本底地区职业性受照免疫增强效应低剂量诱导蛋白基因调控
Keywords:
low dose radiationstimulative effectshigh background radiation areaoccupational irradiationimmunity enhancing effectlow-dose-radiation induced proteinsgene regulation
分类号:
R811.5
摘要:
国内外有关低剂量辐射兴奋效应的研究始于70年代末,近年来已从低剂量诱导蛋白生成、基因调控方面研究其机制。本文分别从流行病学调查和放射生物学研究两大领域对低剂量辐射兴奋效应及其机制加以综述。
Abstract:
Studies related to stimulative effects of low dose radiation began in the late 1970 s.In recent years, these studies have focused on the mechanism of the stimulation through low-dose-radiation induced proteins and gene regulation.This review consists two parts: epidemiological studies and radiobiological studies of stimulative effects of low dose radiation and their mechanism.

参考文献/References:

[1]陶祖范,加藤宽夫,查永如等.阳江高本底地区恶性肿瘤死亡调查1987~1990年资料的初步分析[J].中华放射医学与防护杂志, 1997, 17(6):376-380.
[2]李嘉,官崎弘之,杨宇华等.阳江天然放射性高本底地区老年性痴呆患病率的调查[J].中华放射医学与防 护杂志, 1997, 17(4):271-275.
[3] PierceDA, Preston DL Radiation-related cancer risks at low doses among atomic bomb survivors[J].Radiat Res.2000, 154:178-186.
[4] Tronkko MD, Bogdanova TI, Komissarenko IV, et al.Thyroid carainoma in persons in ukraine after chernobyl nuckear accident.Statistical data and clinicomorphokogic characteristics[J].Cancer, 1999, 86:149-156.
[5] Belyaev IY, Spivak IM, Kolman A, at al.Relationship between radiation induced adaptive response in human fibroblasts and changes in chromatin conformation[J].Mutati Res, 1996, 358:223-225.
[6] Hashimoto S, Shirato H, Hosokawa M, et al.The suppression of metastases and the change in host immune response after low-dose total-body irradiation in tumor-bearing rats[J].Radiati Re, 1999, 151:717-724.
[7] Vykhovanets EV, Chernyshov VP, Slukvin II, et al.Analysis of blood lymphocyte subsets in children living around chernobyl exposed long-term to low doses of cesium-137 and various doses of iodine-131[J].Radiat Res, 2000, 153:760-772.
[8] Igor V, Filippovic H, Natalya I, et al.Radiation-inpuced apoptosis in human tumor cell lines:adaptive response and split-dose effect[J].Int J Cancer, 1998, 77:76-81.
[9] Chmura S, Nodzenki E, Beckett MA, et al.Loss of ceramide production confers resistance to radiation-induced apoptosis[J].Cancer Res, 1997, 57:1270-1275.
[10] Ishiik, Yamaokak, Hosoik, et al.Enhanced mitagen-induced proliferation of rat splenocytes by low dose whole body x-irradiation[J].Chem Phys Med NM R, 1995, 27(1):17-23.
[11] Wolff S.Adapation of human and other mamalian cells to low doses of radiation[J].Radiat Res, 1995, 141:115-117.
[12] Keiji Suzuki, Seji Kodama and Masami Watanabe.Effect of low-dose preirradiation on induction of the HSP70B-Lac Z fusion gene in human cells treated with heat shock[J].Radiat Res, 1998, 149:195-201.
[13] Shatman TD, Saleam A, Kyriakis J, et al.Defertive induction of stress-activated proteinkinase activity in ataxia-telangiestasia cells exposed to ionizing radiation[J].Cancer Res, 1995, 55:3242-3245.
[14] Rigand O, Moustacchi E.Radioadaptation for gene mutation and the possible mechanisms of the adaptive response[J].Mutat Res, 1996, 358(2):127-134.
[15] Sadekova S, Lehnert S and Chow TYK.Induction of PBP74/mortalin/Grp75.A member of HSP70 family by low doses of ionizing radiation:a possible role in induced radioresistance[J].Int J Radiat Biol, 1997, 72 (6):653-660.
[16] Amundson SA, Do KT and Fornace AJ Jr.Induction of stress genes by low doses of gamma rays[J].Radiat Res, 1999, 152:225-231.
[17] Schmidt-Ullrich RK, Valerie K, Fogleman PB, et al.Radiation-induced autophosphorylation of epidermal growth factor recepter in human malignant mammary and squamous epithelial cells[J].Radiat Res, 1996, 145:81-85.
[18] Canman E and Kastan MB.Three paths to stress relief[J].Nature, 1996, 384:213-214.
[19] Porten CS, Wilson JW, Booth C, et al.Regulation and significance of apoptosis in the stem cell of the gastrointestinal epithelium[J].Stem Cell, 1997, 15:87-93.
[20] Zhan Q, Alamo L, Yu K, et al.The apotosis-associatedγ-ray response of Bcl-X 1 depends on normal p53 function[J].Oncogene, 1996, 13:2287-2293.
[21] Mothersill C, Omaney J, Harney J, et al.Futher investigation of the response of human uroepithelium to low dose of Cobalt-60 gamma rays[J].Radiat Res, 1997, 147:156-165.
[22] Harney J, Nurphy D, Jones M, et al.p53 expression in urothelium from normal and tumor bearing patients[J].Br J Cancer, 1995, 71:25-29.
[23] Ohnishi T, Wang X, Takahashi A, et al.Low-dose-rate radiation attenuates the response of the tumor suppressor TP53[J].Radiat Res, 1999, 151:367-372.
[24] Colucci S, Mothersill C, Harney J, et al.Induction of multiple PCR-SSCPE mobility shifts in p53 exons in cultures of normal human urothelium exposed to low-dose radiation[J].Int J Radiat Biol, 1997, 72(1):21-23.

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[6]周平坤,夏寿萱.真核基因损伤修复和基因表达的辐射兴奋效应[J].国际放射医学核医学杂志,1996,20(5):223.

备注/Memo

备注/Memo:
收稿日期:2000-11-05。
作者简介:吕兑财(1965-),男,甘肃静宁人,苏州大学核医学院硕士研究生,主要从事医学放射生物学研究。
更新日期/Last Update: 1900-01-01