[1]韩佩珍.化学发光免疫分析[J].国际放射医学核医学杂志,2000,24(5):196-201.
　HAN Pei-zhen.Chemiluminescence immunoassay[J].International Journal of Radiation Medicine and Nuclear Medicine,2000,24(5):196-201.
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
24
期数:
2000年第5期
页码:
196-201
栏目:
综述
出版日期:
1900-01-01

文章信息/Info

Title:
Chemiluminescence immunoassay
作者:
韩佩珍
300192 天津, 中国医学科学院中国协和医科大学放射医学研究所
Author(s):
HAN Pei-zhen
Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, China
关键词:
化学发光免疫分析; 酶免疫分析; 放射免疫分析
Keywords:
chemiluminescence immunoassay; enzyme immunoassay; radioimmunoassay
分类号:
R446.6
摘要:
化学发光免疫分析技术基于放射免疫分析的基本原理,其特点是以化学发光物质为示踪物,灵敏度高,快速,简便,主要试剂包括氧化剂、发光剂和催化剂等,测试中不使用有害的试剂,因此成为非放射性免疫分析法中最有前途的方法。
Abstract:
An updated immunoassay technology, chemiluminescence immunoassay (CLIA) is presented. The princi-ple of CLIA is based on it of RIA that the immunoreaction is resulted using a tracer labeled by chemiluminescent CLIA is bringing the clinical laboratories into a new generation on higher sensitivity, faster, more convenient, au-tomatic and less hazardous than radioimmunoassay.

参考文献/References:

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[7] Wilkinson E, Rae PW H, Thomson KJT, et al. Chemilu-minescent third-generation assay (Amerlite TSH-30) of thyroid-stimu-lating hormone in serum or plasma assessed[J]. Clin Chem, 1993, 39(10):2166-2173.
[8] Christofides ND and Sheehan CP. Enhanced Chemilu-minescence labeled-antibody immunoassay (Amerlite-MAB) for free thyroxine:design, development, and technical valiation[J]. Clin Chem, 1995, 41(1):17-23.
[9] Brustein I, Edwards Band Voyta JC. 1, 2-Dioxetances:novel chemiluminescent enzyme substrates. Applica-tions to immunoassay[J]. J Biolumin Chemilumin, 1989, 4:99-111.
[10] Patterson W, Werness P, Payne W, et al. Random and continuous-acess immunoassays with chemilumi-nescent detection by acess automated analyzer[J]. Clin Chem, 1994, 40:2042.
[11] David HW, et al. Rapid, automated assay for proges-terone on the Abbott AxSYM analyzer[J]. 1998, 44 (1):86.[12]胡天喜,陈杞,陈克明,等.发光分析与医学[M].上海:华东师范大学出版社, 1990, 167-186.
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备注/Memo

备注/Memo:
收稿日期:2000-08-17。
作者简介:韩佩珍(1942-),女,浙江慈溪人,中国医学科学院中国协和医科大学放射医学研究所研究员,博士生导师,主要从事分子核医学尤其是体外免疫诊断试剂的开发研究。
更新日期/Last Update: 1900-01-01