[1]童冠圣.核素标记微球治疗肝癌的实验与临床研究[J].国际放射医学核医学杂志,2000,24(3):116-119.
　TONG Guan-sheng.Experimental and clinical study on radionuclide-lablled microspheres in treating hepatic cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2000,24(3):116-119.
点击复制

核素标记微球治疗肝癌的实验与临床研究(/HTML)
分享到：

《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
24
期数:
2000年第3期
页码:
116-119
栏目:
综述
出版日期:
1900-01-01

文章信息/Info

Title:
Experimental and clinical study on radionuclide-lablled microspheres in treating hepatic cancer
作者:
童冠圣
210009 南京, 南京铁道医学院现代实验中心放免中心
Author(s):
TONG Guan-sheng
Radioimmunology Center, Modern Medical Research Center, Nanjing Railway Medical College, Jiangsu Nanjing 210009, China
关键词:
肝癌; 核素标记微球; 内照射治疗; 剂量学
Keywords:
liver neoplasms; radionuclide-labelled microspheres; internal radiation therapy; dosage
分类号:
R817. 5
摘要:
简述核素标记微球内照射治疗肝癌的概况,评价各种核素及其微球载体的特点和选择,比较放射性微球治疗肝癌的给药方法及临床疗效,阐述吸收剂量的估算方法和正常肝的耐受剂量。
Abstract:
Briefly described the current states of internal irradiative treatment of hepatic carcinoma with radionuclide-labelled microspheres; Evaluating the characteristics and selection of different radioisotopes and their microsphere carriers; Comparing the method of medication and therapeutic effectiveness of different radiative microspheres in treating hepatic carcinoma; Explained the methods in estimating absorbed dosage and endurable dosage of normal liver.

参考文献/References:

[1] Tian JH, Xu BX, Zhang JM, et al. Ultrasound-guided internal radiotherapy using yttrium-90-glass microsphers for liver malignancies[J]. J Nucl Med,1996, 37:958~963.
[2] Andrews JC, Walker SC, Ackermann RJ, et al. He-patic radioembolization with yttrium-90 containing glass microspheres:preliminary results and clinical follow-up[J]. J Nucl Med, 1994, 35(10):1637~1644.
[3] Lau WY, Ho S, Leung NWY, et al. Selective internal radiation therapy for nonresectable hepatocellular carcinoma with intraarterial infusion of yttrium-90 microsphers[J]. Int J Radiat Oncol Biol Phys, 1998,40(3):583~592.
[4] Teng GJ, Liu L, Fang W. Hepatic malignancies:pilot trial of treatment with phosphorus-32 glass microspheres[J]. JVIR, 1998, 9(1):198~199.
[5] Yan ZP, Lin G, Zhao HY, et al. An experimental study and clinical pilot trials on yttrium-90 glass microspheres through the hepatic artery for the treatment of primary liver cancer[J]. Cancer, 1993,72(11):3210~3215.
[6] Ho S, Lau W Y, Leung W T. Comments on "Ultrasound-guidedinternal radiotherapy using yttrium-90-glass microsphers for liver malignancies."[J]. J Nucl Med, 1997, 38(7):1169~1170.
[7] Liu L, Teng GJ, Fang W. Acute and sub-acute toxic response to intrahepatic arterial administration of phosphorus-32 glass microspheres in pigs[J]. JVIR,1998, 9(1):166.
[8] Gray BN, Burton MA, Kelleher DK, et al. Tolerance of the liver to the effects of yttrium-90 radiation[J].Int J Radiat Oncol Biol Phys, 1990, 18:619~623.
[9] Ho S, Lau WY, Leung TW T, et al. Partition model for estimating radiation doses from yttrium-90 microsphers in treating hepatic cancer[J]. Eur J Nucl Med, 1996, 23:947~952.
[10] Ho S, Lau WY, Leung TW T, et al. Clinical evaluation of the partition model for estimating radiation doses from yttrium-90 microsphers in the treatment of hepatic cancer[J]. Eur J Nucl Med,1997, 24:293~298.
[11] Hafeili UO, Casillas S, Dietz DW, et al. Hepatic tumor radioembolization in a rat model using radioactive rhenium (186Re/188Re) glass microspheres[J]. Int J Radiat Oncol Biol Phys, 1999, 44(1):189~199.
[12] Wang SJ, Lin W Y, Chen MN, et al. Intratumoral injection of rhenium-188 microsphers into an animal model of hepatoma[J]. J Nucl Med, 1998, 39(10):1752~1757.
[13] Nijsen JF,Zonnenberg BA, Woittiez JR, et al.Holmium-166 poly lactic acid microsphers applicable for intra-arterial radionuclide therapy of hepatic malignancies:effects of preparation and neutron activation techniques[J]. Eur J Nucl Med, 1999, 26(7):699~704.
[14] Wunderlich G, Pinkert J, Andreeff M, et al.Preparation and biodistribution of rhenium-188 labelled albumin microspheres B20:a promising new agent for radiotherapy[J]. Appl Radiat Isot. 2000, 52(1):63~68

相似文献/References:

[1]吴震宇.核素显像在肝癌临床诊断中的应用[J].国际放射医学核医学杂志,2004,28(5):199.
　WU Zhen-yu.The clinical application of nuclein scanning in liver carcinoma[J].International Journal of Radiation Medicine and Nuclear Medicine,2004,28(3):199.
[2]温广华.18F-FDG PET显像在肝癌中的应用[J].国际放射医学核医学杂志,2003,27(1):21.
　WEN Guang-hua.The applications of 18F-FDG PET in liver carcinoma[J].International Journal of Radiation Medicine and Nuclear Medicine,2003,27(3):21.
[3]鞠永健.90Y微球治疗肝癌的剂量估算方法现状[J].国际放射医学核医学杂志,2002,26(3):134.
　JU Yong-jian.The methods of dose estimation about the treatment with 90Y-microspheres in liver malignancy[J].International Journal of Radiation Medicine and Nuclear Medicine,2002,26(3):134.
[4]傅尚志,张楚毅.肝癌内照射临床及实验研究进展[J].国际放射医学核医学杂志,1996,20(5):202.

备注/Memo

备注/Memo:
收稿日期:2000-02-01。
基金项目:江苏省科委应用基础项目(BJ93077)
作者简介:童冠圣(1966-),男,安徽寿县人,南京铁道医学院现代医学实验中心放免中心主治医师,硕士研究生,主要从事肿瘤核医学研究。
更新日期/Last Update: 1900-01-01