[1]陈兴,赵军.PET/MR的衰减校正技术[J].国际放射医学核医学杂志,2018,(4):352-356.[doi:10.3760/cma.j.issn.1673-4114.2018.04.012]
 Chen Xing,Zhao Jun.Overview of PET/MR attenuation correction[J].International Journal of Radiation Medicine and Nuclear Medicine,2018,(4):352-356.[doi:10.3760/cma.j.issn.1673-4114.2018.04.012]
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PET/MR的衰减校正技术(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
期数:
2018年第4期
页码:
352-356
栏目:
综述
出版日期:
2018-07-25

文章信息/Info

Title:
Overview of PET/MR attenuation correction
作者:
陈兴 赵军
200123 上海, 同济大学附属东方医院核医学科
Author(s):
Chen Xing Zhao Jun
Department of Nuclear Medicine, Shanghai East Hospital, Tongji University, Shanghai 200123, China
关键词:
正电子发射型计算机断层显像磁共振成像衰减校正地图集法组织分割法发射数据重建法
Keywords:
Positron emission computed tomographyMagnetic resonance imagingAttenuation correctionAtlasTissue segmentationEmission data reconstruction
DOI:
10.3760/cma.j.issn.1673-4114.2018.04.012
摘要:
PET/MR是目前最先进的分子影像设备,PET图像需要通过衰减校正来得到真实的放射性药物活度分布并对其进行量化。笔者主要对PET/MR的衰减校正原理和衰减校正的方法进行综述,重点介绍地图集法、组织分割法和具有发展前景的发射数据重建法。
Abstract:
PET/MR is the most advanced molecular imaging device nowadays. The PET image needs to be quantified by attenuation correction(AC) to obtain the real activity distribution of radioactive drugs. The principle of AC of PET/MR and four methods of AC are briefly described in this paper.This paper mainly introduces the tissue segmentation and atlas method. A more promising launch data reconstruction method is also introduced in this paper.

参考文献/References:

[1] Boss A, Kolb A, Hofmann M, et al. Diffusion tensor imaging in a human PET/MR hybrid system[J]. Invest Radiol, 2010, 45(5):270-274. DOI:10.1097/RLI.0b013e3181dc3671.
[2] 傅磊, 贺建峰. 基于支持向量回归的PET/CT图像衰减校正方法[J]. 北京生物医学工程, 2017, 36(3):245-250. DOI:10.3969/j.issn.1002-3208.2017.03.04. Fu L, He JF. PET/CT imaging attenuation correction method based on support vector regression[J]. Beijing Biomed Eng, 2017, 36(3):245-250.
[3] 高艳,赵晋华. PET/MR衰减校正技术的研究进展[J]. 中国医疗设备,2015, 30(7):75-78. DOI:10.3969/j.issn.1674-1633. 2015. 07.024. Gao Y, Zhao JH. Advances in Development of PET/MR Attenuation Correction Technology[J]. China Med Devices, 2015, 30(7):75-78.
[4] Montandon ML, Zaidi H. Atlas-guided non-uniform attenuation rection in cerebral 3D PET imaging[J]. Neuroimage, 2005, 25(1):278-286. DOI:10.1016/j.neuroimage.2004.11.021.
[5] Hofmann M, Steinke F, Scheel V, et al. MRI-based attenuation correction for PET/MRI:a novel approach combining pattern recognition and atlas registration[J]. J Nucl Med, 2008, 49(11):1875-1883. DOI:10.2967/jnumed.107.049353.
[6] Hofmann M, Pichler B, Schölkopf B, et al. Towards quantitative PET/MRI:a review of MR-based attenuation correction techniques[J]. Eur J Nucl Med Mol Imaging, 2009, 36 Suppl 1:S93-104. DOI:10.1007/s00259-008-1007-7.
[7] Yang J, Jian Y, Jenkins N, et al. Quantitative Evaluation of Atlas-based Attenuation Correction for Brain PET in an Integrated Time-of-Flight PET/MR Imaging System[J]. Radiology, 2017, 284(1):169-179. DOI:10.1148/radiol.2017161603.
[8] Han X. MR-based synthetic CT generation using a deep convolutional neural network method[J]. Med Phys, 2017, 44(4):1408-1419. DOI:10.1002/mp.12155.
[9] Khalifé M, Fernandez B, Jaubert O, et al. Subject-specific bone attenuation correction for brain PET/MR:can ZTE-MRI substitute CT scan accurately?[J]. Phys Med Biol, 2017, 62(19):7814-7832. DOI:10.1088/1361-6560/aa8851.
[10] Sekine T, Burgos N, Warnock G, et al. Multi-Atlas-Based Attenuation Correction for Brain 18F-FDG PET Imaging Using a Time-of-Flight PET/MR Scanner:Comparison with Clinical Single-Atlas-and CT-Based Attenuation Correction[J]. J Nucl Med, 2016, 57(8):1258-1264. DOI:10.2967/jnumed.115.169045.
[11] Huang SC, Carson RE, Phelps ME, et al. A boundary method for attenuation correction in positron computed tomography[J]. J Nucl Med, 1981, 22(7):627-637.
[12] Zaidi H, Montandon ML, Slosman DO. Magnetic resonance imaging-guided attenuation and scatter corrections in three-dimensional brain positron emission tomography[J]. Med Phys, 2003, 30(5):937-948. DOI:10.1118/1.1569270.
[13] Roy S, Wang WT, Carass A, et al. PET attenuation correction using synthetic CT from ultrashort echo-time MR imaging[J]. J Nucl Med, 2014, 55(12):2071-2077. DOI:10.2967/jnumed.114.143958.
[14] An HJ, Seo S, Kang H, et al. MRI-Based Attenuation Correction for PET/MRI Using Multiphase Level-et Method[J]. J Nucl Med, 2016, 57(4):587-593. DOI:10.2967/jnumed.115.163550.
[15] Berker Y, Franke J, Salomon A, et al. MRI-based attenuation correction for hybrid PET/MRI systems:a 4-class tissue segmentation technique using a combined ultrashort-echo-time/Dixon MRI sequence[J]. J Nucl Med, 2012, 53(5):796-804. DOI:10.2967/jnumed.111.092577.
[16] Eiber M, Martinez-Möller A, Souvatzoglou M, et al. Value of a Dixon-based MR/PET attenuation correction sequence for the localization and evaluation of PET-positive lesions[J]. Eur J Nucl Med Mol Imaging, 2011, 38(9):1691-1701. DOI:10.1007/s00259-011-1842-9.
[17] Catana C, van der Kouwe A, Benner T, et al. Toward implementing an MRI-based PET attenuation-correction method for neurologic studies on the MR-PET brain prototype[J]. J Nucl Med, 2010, 51(9):1431-1438. DOI:10.2967/jnumed.109.069112.
[18] Wagenknecht G, Rota KE, Mantlik F, et al. Attenuation correction in MR-Brain PET with segmented T1-weighted MR images of the patient’s head:A comparative study with CT[J]. IEEE Nucl Sci Conf R, Nuclear Science Symposium 2011:2261-2266. DOI:10.1109/NSSMIC.2011.6153858.
[19] Berker Y, Franke J, Salomon A, et al. MRI-based attenuation correction for hybrid PET/MRI systems:a 4-class tissue segmentation technique using a combined ultrashort-echo-time/Dixon MRI sequence[J]. J Nucl Med, 2012, 53(5):796-804. DOI:10.2967/jnumed.111.092577.
[20] Aasheim LB, Karlberg A, Goa PE, et al. PET/MR brain imaging:evaluation of clinical UTE-based attenuation correction[J]. Eur J Nucl Med Mol Imaging, 2015, 42(9):1439-1446. DOI:10.1007/s00259-015-3060-3.
[21] 孙寿伟, 钱鹏江, 胡凌志, 等. 迁移模糊聚类在医学PET/MRI快速衰减校正中的应用[J]. 计算机工程与科学, 2016, 38(4):775-784. DOI:10.3969/j.issn.1007-130X.2016.04.024. Sun SW, Qian PJ, Hu LZ, et al. A transfer fuzzy clustering based fast PET/MRI AC method[J]. Comput Eng Sci, 2016, 38(4):775-784.
[22] Nuyts J, Dupont P, Stroobants S, et al. Simultaneous maximum a posteriori reconstruction of attenuation and activity distributions from emission sinograms[J]. IEEE Trans Med Imaging, 1999, 18(5):393-403. DOI:10.1109/42.774167.
[23] Heuβer T, Rank CM, Berker Y, et al. MLAA-based attenuation correction of flexible hardware components in hybrid PET/MR imaging[J/OL]. EJNMMI Phys, 2017, 4(1):12[2018-04-18]. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC53323221. DOI:10.1186/s40658-017-0177-4.
[24] Nuyts J, Bal G, Kehren F, et al. Completion of a truncated attenuation image from the attenuated PET emission data[J]. IEEE Trans Med Imaging, 2013, 32(2):237-246. DOI:10.1109/TMI.2012. 2220376.
[25] Mollet P, Keereman V, Clementel E, et al. Simultaneous MR-compatible emission and transmission imaging for PET using time-of-flight information[J]. IEEE Trans Med Imaging, 2012, 31(9):1734-1742. DOI:10.1109/TMI.2012.2198831.
[26] Mollet P, Keereman V, Bini J, et al. Improvement of attenuation correction in time-of-flight PET/MR imaging with a positron-emitting source[J]. J Nucl Med, 2014, 55(2):329-336. DOI:10.2967/jnumed.113.125989.

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备注/Memo

备注/Memo:
收稿日期:2018-04-19。
基金项目:上海市浦东新区卫生系统重点专科(PWZzk2017-24)
通讯作者:赵军,Email:petcenter@126.com
更新日期/Last Update: 2018-07-25