[1]杜芬,胡珊,梁梦,等.18F-FDG PET/CT显像在甲状腺偶发瘤良恶性诊断中的研究进展[J].国际放射医学核医学杂志,2018,(3):274-279.[doi:10.3760/cma.j.issn.1673-4114.2018.03.015]
 Du Fen,Hu Shan,Liang Meng,et al.Development in the diagnosis of benign and malignant thyroid incidentalomas by 18F-FDG PET/CT imaging[J].International Journal of Radiation Medicine and Nuclear Medicine,2018,(3):274-279.[doi:10.3760/cma.j.issn.1673-4114.2018.03.015]
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18F-FDG PET/CT显像在甲状腺偶发瘤良恶性诊断中的研究进展(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
期数:
2018年第3期
页码:
274-279
栏目:
综述
出版日期:
2018-05-25

文章信息/Info

Title:
Development in the diagnosis of benign and malignant thyroid incidentalomas by 18F-FDG PET/CT imaging
作者:
杜芬1 胡珊1 梁梦1 程艳12
1. 030001 太原, 山西医科大学第一医院核医学科;
2. 030001 太原, 山西省分子影像精准诊疗协同创新中心
Author(s):
Du Fen1 Hu Shan1 Liang Meng1 Cheng Yan12
1. Department of Nuclear Medicine, First Hospital of Shanxi Medical University, Taiyuan 030001, China;
2. Molecular Imaging Precision Medicine Collaborative Innovation Center of Shanxi Province, Taiyuan 030001, China
关键词:
甲状腺肿瘤氟脱氧葡萄糖F18正电子发射断层显像计算机体层摄影术
Keywords:
Thyroid neoplasmsFluorodeoxyglucose F18Positron emission tomography computed tomography
DOI:
10.3760/cma.j.issn.1673-4114.2018.03.015
摘要:
PET/CT作为一种集功能代谢及解剖形态信息于一身的影像学诊断方法,在疾病良恶性诊断、肿瘤分期与再分期和疗效与预后评价中的应用越来越广泛。目前,甲状腺偶发瘤的发现愈来愈多,引起了临床医师的密切关注。笔者分别就PET/CT检查中发现的局灶性及弥漫性甲状腺偶发瘤的发生率、恶性率、良恶性病变的影像学特征及研究新进展等方面进行综述。
Abstract:
PET/CT is an imaging technique that integrates the functional metabolism and anatomical morphological information. This technology has been widely applied in differentiating malignant and benign tumors, cancer staging and restaging, and monitoring treatment response and prognosis. PET/CT has attracted considerable attention among clinicians because of the increasing number of thyroid incidentalomas. This article presents a review of the incidence, malignant rate, imaging features, and latest development of focal and diffuse thyroid incidentalomas using PET/CT imaging studies.

参考文献/References:

[1] Soelberg KK, Bonnema SJ, Brix TH, et al. Risk of malignancy in thyroid incidentalomas detected by 18F-fluorodeoxyglucose positron emission tomography: a systematic review[J]. Thyroid, 2012, 22(9):918-925. DOI:10.1089/thy.2012.0005.
[2] Bae JS, Chae BJ, Park WC, et al. Incidental thyroid lesions detected by FDG-PET/CT:prevalence and risk of thyroid cancer[J]. World J Surg Oncol, 2009, 7:63. DOI:10.1186/1477-7819-7-63.
[3] Pampaloni MH, Win AZ. Prevalence and Characteristics of Incidentalomas Discovered by Whole Body FDG PETCT[J]. Int J Mol Imaging, 2012, 2012:476763. DOI:10.1155/2012/476763.
[4] Nakamoto Y, Tatsumi M, Hammoud D, et al. Normal FDG distribution patterns in the head and neck:PET/CT evaluation[J]. Radiology, 2005, 234(3):879-885. DOI:10.1148/radiol.2343030301.
[5] Han YM, Kim YC, Park EK, et al. Diagnostic value of CT density in patients with diffusely increased FDG uptake in the thyroid gland on PET/CT images[J]. AJR Am J Roentgenol, 2010, 195(1):223-228. DOI:10.2214/AJR.09.3319.
[6] Soelberg KK, Bonnema SJ, Brix TH, et al. Risk of malignancy in thyroid incidentalomas detected by 18F-fluorodeoxyglucose positron emission tomography:a systematic review[J]. Thyroid, 2012, 22(9):918-925. DOI:10.1089/thy.2012.0005.
[7] Chun AR, Jo HM, Lee SH, et al. Risk of malignancy in thyroid incidentalomas identified by fluorodeoxyglucose-positron emission tomography[J]. Endocrinol Metab (Seoul), 2015, 30(1):71-77. DOI:10.3803/EnM.2015.30.1.71.
[8] Chen W, Zheng R, Baade PD, et al. Cancer statistics in China, 2015[J]. CA Cancer J Clin, 2016, 66(2):115-132. DOI:10.3322/caac.21338.
[9] Czepczyński R, Stangierski A, Oleksa R, et al. Incidental 18F-FDG uptake in the thyroid in patients diagnosed with PET/CT for other malignancies[J]. Nucl Med Rev Cent East Eur, 2011, 14(2):68-72. DOI:10.5603/NMR.2011.00018.
[10] Barrio M, Czernin J, Yeh MW, et al. The incidence of thyroid cancer in focal hypermetabolic thyroid lesions:an 18F-FDG PET/CT study in more than 6000 patients[J]. Nucl Med Commun, 2016, 37(12):1290-1296. DOI:10.1097/MNM.0000000000000592.
[11] Pattison DA, Bozin M, Gorelik A, et al. 18F-fluorodeoxyglycose-avid thyroid incidentalomas:the importance of contextual interpretation[J/OL]. J Nucl Med, 2017[2017-10-24]. http://jnm.snmjournals.org/content/early/2017/10/11/jnumed.117.198085. DOI:10.2967/jnumed.117.198085.
[12] Hagenimana N, Dallaire J, Vallée É, et al. Thyroid incidentalomas on 18FDG-PET/CT: a metabolico-pathological correlation[J]. J Otolaryngol Head Neck Surg, 2017, 46(1):22. DOI:10.1186/s40463-017-0200-8.
[13] Lee WM, Kim BJ, Kim MH, et al. Characteristics of thyroid incidentalomas detected by pre-treatment 18F-FDG PET or PET/CT in patients with cervical cancer[J]. J Gynecol Oncol, 2012, 23(1):43-47. DOI:10.3802/jgo.2012.23.1.43.
[14] Chen YK, Ding HJ, Chen KT, et al. Prevalence and risk of cancer of focal thyroid incidentaloma identified by 18F-fluorodeoxyglucose positron emission tomography for cancer screening in healthy subjects[J]. Anticancer Res, 2005, 25(2B):1421-1426.
[15] Sharma SD, Jacques T, Smith S, et al. Diagnosis of incidental thyroid nodules on 18F-fluorodeoxyglucose positron emission tomography imaging: are these significant?[J]. J Laryngol Otol, 2015, 129(1):53-56. DOI:10.1017/S0022215114003107.
[16] Ho TY, Liou MJ, Lin KJ, et al. Prevalence and significance of thyroid uptake detected by 18F-FDG PET[J]. Endocrine, 2011, 40(2):297-302. DOI:10.1007/s12020-011-9470-5.
[17] Choi JY, Lee KS, Kim HJ, et al. Focal thyroid lesions incidentally identified by integrated 18F-FDG PET/CT:clinical significance and improved characterization[J]. J Nucl Med, 2006, 47(4):609-615.
[18] Agrawal K, Weaver J, Ngu R, et al. Clinical significance of patterns of incidental thyroid uptake at 18F-FDG PET/CT[J]. Clin Radiol, 2015, 70(5):536-543. DOI:10.1016/j.crad.2014.12.020.
[19] 李雪娜, 尹雅芙, 杜补林, 等. 18F-FDG PET/CT显像偶发甲状腺癌的葡萄糖代谢与临床病理学的相关性研究[J]. 中国癌症杂志, 2016, 26(6):527-532. DOI:10.19401/j.cnki.1007-3639. 2016. 06. 008. Li XN, Yin YF, Du BL, et al.The correlation study between the glucose metabolism of 18F-FDG PET/CT incidental thyroid cancer and clinicopathologic characteristics[J]. Chin Oncol, 2016, 26(6):527-532.
[20] Demir Ö, Köse N,Özkan E, et al. Clinical significance of thyroid incidentalomas identified by 18F-FDG PET/CT: correlation of ultrasonograpy findings with cytology results[J]. Nucl Med Commun, 2016, 37(7):715-720. DOI:10.1097/MNM.0000000000000495.
[21] Kang KW, Kim SK, Kang HS, et al. Prevalence and risk of cancer of focal thyroid incidentaloma identified by 18F-fluorodeoxyglucose positron emission tomography for metastasis evaluation and cancer screening in healthy subjects[J]. J Clin Endocrinol Metab, 2003, 88(9):4100-4104. DOI:10.1210/jc.2003-030465.
[22] Bonabi S, Schmidt F, Broglie MA, et al. Thyroid incidentalomas in FDG-PET/CT: prevalence and clinical impact[J]. Eur Arch Otorhinolaryngol, 2012, 269(12):2555-2560. DOI:10.1007/s00405-012-1941-7.
[23] Mirza AA, Pai E, Srinivas KG, et al. Diagnostic Dilemma in a Thyroid Incidentaloma: Second Primary versus Metastatic Nodule?[J]. J Clin Diagn Res, 2016, 10(6):PD10-12. DOI:10.7860/JCDR/2016/18279.8011.
[24] 王佩国, 王平. 甲状腺转移癌(附9例报告)[J]. 中国肿瘤临床, 2005, 32(13):775-776. DOI:10.3969/j.issn.1000-8179. 2005.13. 016. Wang PG, Wang P. Metaset carcinoma of the thyroids[J]. Chin J Clin Oncol, 2005, 32(13):775-776.
[25] Osawa M, Takigawa N, Kiura K, et al. Isolated metastasis of lung cancer to the thyroid gland[J]. Lung Cancer, 2007, 58(1):156-158. DOI:10.1016/j.lungcan.2007.04.014.
[26] Lam KY, Lo CY. Metastatic tumors of the thyroid gland:a study of 79 cases in Chinese patients[J]. Arch Pathol Lab Med, 1998, 122(1):37-41.
[27] Thuillier P, Roudaut N, Crouzeix G, et al. Malignancy rate of focal thyroid incidentaloma detected by FDG PET-CT: results of a prospective cohort study[J]. Endocr Connect, 2017, 6(6):413-421. DOI:10.1530/EC-17-0099.
[28] Targe M, Basu S. Focal thyroid incidentaloma on whole body fluorodeoxyglucose positron emission tomography/computed tomography in known cancer patients:A case-based discussion with a series of three examples[J]. J Cancer Res Ther, 2015, 11(4):1029. DOI:10.4103/0973-1482.154029.
[29] 吴江, 朱虹, 王新刚, 等. 18F-FDG PET/CT显像在甲状腺病变的应用:与病理对比分析[J]. 中国临床医学影像杂志, 2013, 24(4):242-246. DOI:10.3969/j.issn.1008-1062.2013.04.006. Wu J, Zhu H, Wang XG, et al. Application of 18F-FDG PET/CT in thyroid disease and correlative with histopathological results[J]. J Chin Clin Med Imaging, 2013, 24(4):242-246.
[30] Agrawal K, Weaver J, Ul-Hassan F, et al. Incidence and Significance of Incidental Focal Thyroid Uptake on 18F-FDG PET Study in a Large Patient Cohort: Retrospective Single-Centre Experience in the United Kingdom[J]. Eur Thyroid J, 2015, 4(2):115-122. DOI:10.1159/000431319.
[31] Qu N, Zhang L, Lu ZW, et al. Risk of malignancy in focal thyroid lesions identified by 18F-fluorodeoxyglucose positron emission tomography or positron emission tomography/computed tomography:evidence from a large series of studies[J]. Tumour Biol, 2014, 35(6):6139-6147. DOI:10.1007/s13277-014-1813-4.
[32] Bertagna F, Treglia G, Piccardo A, et al. Diagnostic and clinical significance of 18F-FDG-PET/CT thyroid incidentalomas[J]. J Clin Endocrinol Metab, 2012, 97(11):3866-3875. DOI:10.1210/jc.2012-2390.
[33] Pattison DA, Bozin M, Gorelik A, et al. 18F-fluorodeoxyglycose-avid thyroid incidentalomas:the importance of contextual interpretation[J/OL]. J Nucl Med, 2017[2017-10-23]. http://jnm.snmjournals.org/content/early/2017/10/11/jnumed.117.198085. DOI:10.2967/jnumed.117.198085.
[34] Makis W, Ciarallo A. Thyroid Incidentalomas on 18F-FDG PET/CT:Clinical Significance and Controversies[J]. Mol Imaging Radionucl Ther, 2017, 26(3):93-100. DOI:10.4274/mirt.94695.
[35] Hagenimana N, Dallaire J, Vallée É, et al. Thyroid incidentalomas on 18FDG-PET/CT: a metabolico-pathological correlation[J]. J Otolaryngol Head Neck Surg, 2017, 46(1):22. DOI:10.1186/s40463-017-0200-8.
[36] Yaylali O, Kirac FS, Yuksel D, et al. Evaluation of focal thyroid lesions incidentally detected in fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography images[J]. Indian J Cancer, 2014, 51(3):236-240. DOI:10.4103/0019-509X.146737.
[37] Lee S, Park T, Park S, et al. The Clinical Role of Dual-Time-Point 18F-FDG PET/CT in Differential Diagnosis of the Thyroid Incidentaloma[J]. Nucl Med Mol Imaging, 2014, 48(2):121-129. DOI:10.1007/s13139-013-0247-z.
[38] D’Souza MM, Marwaha RK, Sharma R, et al. Prospective evaluation of solitary thyroid nodule on 18F-FDG PET/CT and high-resolution ultrasonography[J]. Ann Nucl Med, 2010, 24(5):345-355. DOI:10.1007/s12149-010-0357-y.
[39] Kim SJ, Kim BH, Jeon YK, et al. Limited diagnostic and predictive values of dual-time-point 18F FDG PET/CT for differentiation of incidentally detected thyroid nodules[J]. Ann Nucl Med, 2011, 25(5):347-353. DOI:10.1007/s12149-011-0468-0.
[40] Hsiao YC, Wu PS, Chiu NT, et al. The use of dual-phase 18F-FDG PET in characterizing thyroid incidentalomas[J]. Clin Radiol, 2011, 66(12):1197-1202. DOI:10.1016/j.crad.2011.08.005.
[41] 陈聪霞, 李文婵, 刘甫庚, 等. 腺癌性孤立性肺结节的18F-FDG PET/CT表现[J]. 中华核医学与分子影像杂志, 2011, 31(6):382-385. DOI:10.3760/cma.j.issn.0253-9780.2011.06.008. Chen CX, Li WC, Liu PG, et al. The features of solitary pulmonary nodules of adenocarcinoma on 18F-FDG PET/CT[J]. Chin J Nucl Med Mol Imaging, 2011, 31(6):382-385.
[42] 沈伟明, 张黄华, 倪耿欢. 多层螺旋CT对甲状腺良恶性肿瘤的诊断及鉴别诊断价值[J]. 医学影像学杂志, 2015, 25(9):1690-1692. Shen WM, Zhang HH, Ni GH. The value of MSCT in diagnosis and differential diagnosis of benign and malignant thyroid tumors[J]. J Med Imaging, 2015, 25(9):1690-1692.
[43] Bakhshayesh KM, Doroudinia A, Joukar F, et al. Hypermetabolic Thyroid Incidentaloma on Positron Emission Tomography:Review of Laboratory, Radiologic, and Pathologic Characteristics[J/OL]. J Thyroid Res, 2017, 2017:7176934[2017-10-24]. https://www.hindawi.com/journals/jtr/2017/7176934. DOI:10.1155/2017/7176934.
[44] 关志伟,徐白萱,陈英茂,等. 大规模人群FDG PET/CT意外发现甲状腺高代谢结节的回顾性分析[J]. 中华核医学与分子影像杂志, 2012, 32(1):32-35. DOI:10.3760/cma.j.issn.2095-2848. 2012.01.010. Guan ZW, Xu BX, Chen YM, et al. Retrospective evaluation of focal hypermetabolic thyroid nodules incidentally identified by 18F-FDG PET/CT in a large population[J]. Chin J Nucl Med Mol Imaging, 2012, 32(1):32-35.
[45] 马春旭,袁卫红. 甲状腺结节影像学诊断研究进展[J]. 国际放射医学核医学杂志, 2014, 38(1):48-52. DOI:10.3760/cma.j.issn1673-4114.2014.01.010. Ma CX, Yuan WH. Advanced research on imaging diagnosis of thyroid nodule[J]. Int J Radiat Med Nucl Med, 2014, 38(1):48-52.
[46] 韩志江, 项晶晶, 包凌云, 等. 甲状腺钙化性病变的超声和CT联合诊断[J].国际放射医学核医学杂志, 2016, 39(4):416-421. DOI:10.19300/j.2016.J4246. Han ZJ, Xiang JJ, Bao LY, et al. Combined ultrasound and CT in diagnosis of thyroid calcified lesions[J]. Int J Radiat Med Nucl Med, 2016, 39(4):416-421.
[47] 朱林波, 王淑侠, 徐卫平, 等. 18F-氟代脱氧葡萄糖正电子成像术/计算机断层扫描对甲状腺结节鉴别诊断的价值[J]. 中华诊断学电子杂志, 2014, 2(4):249-251. DOI:10. 3877/cma.j.issn.2095655X. 2014. 04. 002. Zhu LB, Wang SX, Xu WP, et al. Diagnostic vaule of 18F-FDG PET/CT in the differential diagnosis of thyroid nodules[J]. Chin J Diagnostics (Electronic Edition), 2014, 2(4):249-251.
[48] Kim TH, Ji YB, Song CM, et al. SUVmax of 18F-FDG PET/CT in the differential diagnosis of benign and malignant thyroid nodules according to tumor volume[J]. World J Surg Oncol, 2015, 13:217. DOI:10.1186/s12957-015-0635-1.
[49] 郑冬, 牛力璇, 田嘉禾, 等. 18F-FDG PET/CT最大标准化摄取值与舌鳞状细胞癌临床特征的关系[J]. 中国医学影像学杂志, 2017, 25(7):481-486. DOI:10.3969/j.issn.1005-5185.2017.07.001. Zheng D, Niu LX, Tian JH, et al. Relationship between maximum standardized uptake value of 18F-FDG PET/CT and clinical features of tongue squamous cell carcinoma[J]. Chin J Med Imaging, 2017, 25(7):481-486.
[50] Brindle R, Mullan D, Yap BK, et al. Thyroid incidentalomas discovered on positron emission tomography CT scanning-Malignancy rate and significance of standardised uptake values[J]. Eur J Surg Oncol, 2014, 40(11):1528-1532. DOI:10.1016/j.ejso.2014.05.005.
[51] Rothman IN, Middleton L, Stack BC, et al. Incidence of diffuse FDG uptake in the thyroid of patients with hypothyroidism[J]. Eur Arch Otorhinolaryngol, 2011, 268(10):1501-1504. DOI:10.1007/s00405-011-1512-3.
[52] Kurata S, Ishibashi M, Hiromatsu Y, et al. Diffuse and diffuse-plus-focal uptake in the thyroid gland identified by using FDG-PET:prevalence of thyroid cancer and Hashimoto’s thyroiditis[J]. Ann Nucl Med, 2007, 21(6):325-330. DOI:10.1007/s12149-007-0030-2.
[53] Yang Z, Shi W, Zhu B, et al. Prevalence and risk of cancer of thyroid incidentaloma identified by fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography[J]. J Otolaryngol Head Neck Surg, 2012, 41(5):327-333.
[54] Resende de Paiva C, Grønhøj C, Feldt-Rasmussen U, et al. Association between Hashimoto’s Thyroiditis and Thyroid Cancer in 64,628 Patients[J]. Front Oncol, 2017, 7:53. DOI:10.3389/fonc.2017.00053.
[55] Avgoustou C, Avgoustou E. Coexistence of Hashimoto’s thyroiditis and papillary thyroid carcinoma[J]. Hellenic J Surg, 2017, 89(2):73-78. DOI:10.1007/s13126-017-0387-1.
[56] Lai X, Xia Y, Zhang B, et al. A meta-analysis of Hashimoto’s thyroiditis and papillary thyroid carcinoma risk[J]. Oncotarget, 2017, 8(37):62414-62424. DOI:10.18632/oncotarget.18620.

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 Li Shengxu,Tang Mingdeng,Lin Duanyu,et al.Value of 18F-FDG PET/CT in detecting metastatic lymph nodes of thoracic esophageal squamous cell carcinoma[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(3):408.[doi:10.3760/cma.j.issn.1673-4114.2016.06.002]
[10]张莹莹,王振光,武凤玉,等.特发性肺间质纤维化HRCT病变区与非病变区18F-FDG PET/CT表现分析[J].国际放射医学核医学杂志,2016,40(6):414.[doi:10.3760/cma.j.issn.1673-4114.2016.06.003]
 Zhang Yingying,Wang Zhenguang,Wu Fengyu,et al.18F-FDG PET/CT imaging analysis of regions with abnormal and normal pulmonary parenchyma on high resolution CT in idiopathic pulmonary fibrosis patients[J].International Journal of Radiation Medicine and Nuclear Medicine,2016,40(3):414.[doi:10.3760/cma.j.issn.1673-4114.2016.06.003]
[11]胡斌,王锦锋,毛秋粉.18F-FDG PET/CT显像在Tg阳性131I全身显像阴性的分化型甲状腺癌患者中的应用价值[J].国际放射医学核医学杂志,2015,39(3):242.[doi:10.3760/cma.j.issn.1673-4114.2015.03.012]
 Hu Bin,Wang Jinfeng,Mao Qiufen.The application value of 18F-FDG PET/CT in patients with differentiated thyroid cancer of high thyroglobulin level and negative 131I whole body scan[J].International Journal of Radiation Medicine and Nuclear Medicine,2015,39(3):242.[doi:10.3760/cma.j.issn.1673-4114.2015.03.012]

备注/Memo

备注/Memo:
收稿日期:2017-10-24。
通讯作者:程艳,Email:chengyan_1976@163.com
更新日期/Last Update: 2018-05-25