[1]朱磊,陈薇,宋秀宇,等.18F-FDG PET/CT鉴别诊断多系统累及的结节病[J].国际放射医学核医学杂志,2018,(1):90-94.[doi:10.3760/cma.j.issn.1673-4114.2018.01.018]
　Zhu Lei,Chen Wei,Song Xiuyu,et al.Differentiatial diagnosis of sarcoidosis involving multiple systems using 18F-FDG PET/CT[J].International Journal of Radiation Medicine and Nuclear Medicine,2018,(1):90-94.[doi:10.3760/cma.j.issn.1673-4114.2018.01.018]
点击复制

18F-FDG PET/CT鉴别诊断多系统累及的结节病(/HTML)
分享到：

《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
期数:
2018年第1期
页码:
90-94
栏目:
疑难病案分析
出版日期:
2018-03-20

文章信息/Info

Title:
Differentiatial diagnosis of sarcoidosis involving multiple systems using 18F-FDG PET/CT
作者:
朱磊;  陈薇;  宋秀宇;  于筱舟;  黄慧;  刘晓园;  杨震;  徐文贵
300060, 天津医科大学肿瘤医院分子影像及核医学诊疗科
Author(s):
Zhu Lei;  Chen Wei;  Song Xiuyu;  Yu Xiaozhou;  Huang Hui;  Liu Xiaoyuan;  Yang Zhen;  Xu Wengui
Department of Molecular Imaging and Nuclear Medicine, Tianjin Medical University Cancer Institute and Hospital, Tianjin 300060, China
DOI:
10.3760/cma.j.issn.1673-4114.2018.01.018
摘要:
结节病是一种病因不明、可侵犯全身多个器官的系统性疾病。病理特点为非干酪样肉芽肿性炎，可累及淋巴结、肺、肝脏、脾脏、心脏、肾脏、眼、胸膜、心包膜、涎腺、胃肠道、骨、骨髓、皮肤及肌肉等多脏器，其中最常累及部位为淋巴结和肺。典型结节病的影像学表现为纵隔及双肺门淋巴结对称性肿大，伴或不伴有肺侵犯。不典型的、多系统累及的结节病在临床影像诊断中常常与其他多系统受累疾病难于鉴别。笔者选取2例18 F-FDG PET/CT显像中不易于与恶性淋巴瘤、肺癌伴多发转移相鉴别的多系统累及结节病，从其临床特点及影像学特征等方面进行鉴别诊断，总结分析诊断思路，为临床工作中得出较为准确的影像学诊断提供帮助。
Abstract:
Sacoidosis is a systematic disease that can involve multiple organs including lymph nodes, lungs, liver, spleen, heart and kidneys, etc. Lymph nodes and lungs are the most common involved places and lymphadenopathy in the mediastinum and bilateral hilum with or without lung invasion is the typical manifestation. It is difficult to differentiate the atypical sarcoidosis and other multiple systems involved disease, such as lymphoma, tuberculosis and lung cancer with metastasis. Two cases and their PET/CT imaging were presented here to discuss and help with differentiation and diagnosis of sarcoidosis in clinical practice.

参考文献/References:

[1] Sobic-Saranovic D, Grozdic I, Videnovic-Ivanov J, et al. The utility of 18F-FDG PET/CT for diagnosis and adjustment of therapy in patients with active chronic sarcoidosis[J]. J Nucl Med, 2012, 53(10):1543-1549. DOI:10.2967/jnumed.112.104380.
[2] Al-Kofahi K, Korsten P, Ascoli C, et al. Management of extrapulmonary sarcoidosis:challenges and solutions[J]. Ther Clin Risk Manag, 2016, 12:1623-1634. DOI:10.2147/TCRM.S74476.
[3] 张悦,高硕, 李祖贵, 等. 结节病18F-FDG PET/CT显像误诊为淋巴瘤一例[J]. 中华核医学杂志, 2006, 26(6):375. DOI:10.3760/cma.j.issn.2095-2848.2006.06.023. Zhang Y, Gao S, Li ZG, et al. Misdiagnosis of sarcoidosis with lymphoma using 18F-FDG PET/CT[J]. Chin J Nucl Med, 2006, 26(6):375.
[4] Mostard RL, Prompers L, Weijers RE, et al. 18F-FDG PET/CT for detecting bone and bone marrow involvement in sarcoidosis patients[J]. Clin Nucl Med, 2012, 37(1):21-25. DOI:10.1097/RLU.0b013e3182335f9b.
[5] Keijsers RG, Verzijlbergen FJ, Oyen WJ, et al. 18F-FDG PET, genotype-corrected ACE and sIL-2R in newly diagnosed sarcoidosis[J]. Eur J Nucl Med Mol Imaging, 2009, 36(7):1131-1137. DOI:10.1007/s00259-009-1097-x.

备注/Memo

备注/Memo:
收稿日期:2017-11-03。
通讯作者:徐文贵,Email:wenguixy@163.com
更新日期/Last Update: 2018-03-20