[1]南楠,朱小华.分化型甲状腺癌131I显像假阳性的原因分析[J].国际放射医学核医学杂志,2018,(1):62-68.[doi:10.3760/cma.j.issn.1673-4114.2018.01.012]
 Nan Nan,Zhu Xiaohua.Analysis of the false positive findings on 131I whole-body scan in differentiated thyroid cancer[J].International Journal of Radiation Medicine and Nuclear Medicine,2018,(1):62-68.[doi:10.3760/cma.j.issn.1673-4114.2018.01.012]
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分化型甲状腺癌131I显像假阳性的原因分析(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
期数:
2018年第1期
页码:
62-68
栏目:
综述
出版日期:
2018-03-20

文章信息/Info

Title:
Analysis of the false positive findings on 131I whole-body scan in differentiated thyroid cancer
作者:
南楠 朱小华
430030 武汉, 华中科技大学同济医学院附属同济医院核医学科
Author(s):
Nan Nan Zhu Xiaohua
Department of Nuclear Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
关键词:
分化型甲状腺癌碘放射性同位素全身显像体层摄影术发射型计算机单光子假阳性
Keywords:
Differentiated thyroid carcinomaIodine radioisotopesWhole body scanTomographyemission-computedsingle-photonFalse positive
DOI:
10.3760/cma.j.issn.1673-4114.2018.01.012
摘要:
分化型甲状腺癌患者131I全身显像及SPECT显像对于判定病情、决定下一步治疗方案具有重要意义。然而,显像有时会出现假阳性结果,即异常浓聚灶并不是残留的甲状腺组织或甲状腺癌转移灶。系统全面地了解这些假阳性分布及原因有助于图像的准确判读,更可避免患者后续不必要或过大剂量的131I治疗。笔者就分化型甲状腺癌131I全身显像假阳性情况分布、特点及其可能的机制展开综述。
Abstract:
131I whole-body scan and SPECT imaging in patients with differentiated thyroid cancer can provide information regarding metastasis and prognosis, and assist in treatment planning. However, false positive uptake, which is not residual thyroid tissue or metastases, is sometimes encountered. Unless recognized as a false positive, 131I uptake may result in diagnostic error and lead to administration of an unnecessary therapeutic dose. This review discussed various possibilities of false positive uptake on 131I whole-body scan, as well as the underlying causes and mechanisms.

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备注/Memo

备注/Memo:
收稿日期:2017-11-03。
基金项目:国家自然科学基金面上项目(81671718,81271600);湖北省自然科学基金面上项目(2016CFB687)
通讯作者:朱小华,Email:evazhu@vip.sina.com
更新日期/Last Update: 2018-03-20