[1]林小敏,唐明灯,倪雷春.99Tcm-DTPA肾动态显像在根治性肾切除术中的应用价值[J].国际放射医学核医学杂志,2017,41(5):331-334.[doi:10.3760/cma.j.issn.1673-4114.2017.05.005]
 Lin Xiaomin,Tang Mingdeng,Ni Leichun.Application value of renal dynamic imaging in radical nephrectomy[J].International Journal of Radiation Medicine and Nuclear Medicine,2017,41(5):331-334.[doi:10.3760/cma.j.issn.1673-4114.2017.05.005]
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99Tcm-DTPA肾动态显像在根治性肾切除术中的应用价值(/HTML)
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《国际放射医学核医学杂志》[ISSN:1673-4114/CN:12-1381/R]

卷:
41
期数:
2017年第5期
页码:
331-334
栏目:
论著
出版日期:
2017-09-25

文章信息/Info

Title:
Application value of renal dynamic imaging in radical nephrectomy
作者:
林小敏 唐明灯 倪雷春
350014 福州, 福建省肿瘤医院(福建医科大学附属肿瘤医院)核医学科
Author(s):
Lin Xiaomin Tang Mingdeng Ni Leichun
Department of Nuclear Medicine, Fujian Province Tumor Hospital(the Tumor Hospital Affliated to Fujian Medical University), Fuzhou 350014, China
关键词:
肾小球滤过率肾功能不全根治性肾切除术99m锝五乙酸盐肾动态显像
Keywords:
Glomerular filtration rateRenal insufficiencyRadical nephrectomy99Tcm-DTPARenal dynamic imaging
DOI:
10.3760/cma.j.issn.1673-4114.2017.05.005
摘要:
目的 通过99Tcm-DTPA肾动态显像测定总肾及分肾肾小球滤过率(GFR),评价其在根治性肾切除术中的应用价值。方法 60例根治性肾切除术患者术前行99Tcm-DTPA肾动态显像,定量测得总肾及分肾GFR。依据肾脏肿瘤直径大小分为 ≥ 4 cm组和<4 cm组,以了解术前患者GFR降低与肿瘤大小的相关性。采用t检验进行两组GFR水平的比较。单因素及多因素回归分析寻找术后肾功能不全的预测因子。结果 肿瘤<4 cm组患侧平均GFR为(52.94±8.57)mL/min,≥ 4 cm组患侧平均GFR为(45.78±13.27)mL/min,两组术前患侧GFR水平的差异有统计学意义(t=2.152,P<0.05)。术前总GFR水平、术前健侧GFR水平的差异均无统计学意义(t=1.852、1.255,均P>0.05)。术后新出现肾功能不全的比例为21.6%,单因素及多因素logistic回归分析结果发现,术前健侧GFR降低(OR=3.6,P<0.05)、术前总肾GFR降低(OR=5.64,P<0.05)是术后肾功能不全的独立危险因素。结论 采用99Tcm-DTPA肾动态显像可以定量评价分肾和总肾GFR,对肾脏肿瘤患者术前指导及术后肾功能不全的预测有重要的临床意义。
Abstract:
Objective To evaluate the clinical value of total and half glomerular filtration rate (GFR) measured through 99Tcm-DTPA renal dynamic imaging during radical nephrectomy. Methods The total and half GFRs of 60 patients with renal tumors were measured and analyzed through renal dynamic imaging prior to surgery. The patients were divided into two groups in accordance with renal tumor diameter (≥ 4 cm or <4 cm). Then, the correlation between decreased preoperative GFR and tumor size was determined. Univariate and multivariate analyses were performed to detect the predictors of renal insufficiency for the evaluation of the clinical value of total and half GFRs in operated patients. Results The average GFR of the affected kidney in the group with tumors less than 4 cm in diameter was (52.94±8.57) mL/min, whereas that of the group with tumors greater than 4 cm in diameter was (45.78±13.27) mL/min. The preoperative GFR of the affected side (t=2.152, P<0.05) of the two groups were significantly different. Meanwhile, the preoperative GFR of the unaffected side and total kidney of the two groups were not significantly different (t=1.852, 1.255, both P>0.05). The ratio of postoperative new renal insufficiency was 21.6%. Univariate and multivariate analyses showed that the decreased preoperative GFR of the unaffected side (OR=3.6, P<0.05) and total kidney (OR=5.64, P<0.05) are independent risk factors of postoperative renal insufficiency. Conclusion Total and half renal functions determined through renal dynamic imaging are clinically valu- able in the preoperative direction and evaluation of renal insufficiency.

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备注/Memo

备注/Memo:
收稿日期:2017-06-03。
通讯作者:唐明灯,Email:tmd0603@126.com
更新日期/Last Update: 2017-09-25